Feeding leucine and KIC increased plasma HMB levels to that seen when HMB is fed. Feeding IVA also increased HMB suggesting nonoxygenase conversion to HMB.
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1993
Change in plasma ß-hydroxy-ß-methylbutyrate (HMB) by feeding leucine, alpha-ketoisocaproate (KIC), and isovaleric acid (IVA) to pigs
Effect of feeding ß-hydroxy-ß-methylbutyrate (HMB) on leucine and fat metabolism in mammary gland
HMB increased milk fat percentage in lactating goats.
Uptake and output of the leucine metabolite ß-hydroxy-ß-methylbutyrate (HMB) across the leg of pigs
HMB is produced across the hind legs of pigs when high levels of leucine are fed.
Effect of ß-hydroxy-ß-methylbutyrate on the health and performance of shipping stressed calves
HMB decreased morbidity by 40 percent and mortality by 50 percent in young stressed calves (four studies).
