A recent review published in Nutrients provides new support for HMB (β-hydroxy β-methylbutyrate) as a clinically relevant nutritional tool for managing sarcopenia, a condition that has now been officially recognized as a disease under the ICD-10 classification system.  

What is Sarcopenia and Why Classification Matters 

Sarcopenia is the age-related decline in skeletal muscle mass and strength. Its classification as a disease under the ICD-10 framework marks an important shift in how clinicians and researchers approach muscle loss in older adults. Rather than viewing it as an inevitable part of aging, sarcopenia is now treated as a condition with identifiable causes, measurable outcomes, and effective interventions—including nutritional support. 

This recognition is particularly important because sarcopenia is strongly linked to increased risks of falls, frailty, hospitalization, and long-term care. Addressing it early with clinically supported strategies could help reduce healthcare burdens and improve quality of life for older adults. 

What the Latest Research Says About HMB

The new review in Nutrients puts a spotlight on HMB as a standout ingredient for managing sarcopenia and muscle support. Researchers explain that HMB helps your body boost muscle growth and prevent muscle breakdowns that happen more quickly as we age. It’s also known to help reduce inflammation and oxidative stress, both of which can speed up muscle loss over time. In short, HMB gives your muscles the extra support they need when your body’s under more strain than usual. 

To see real benefits, the research points to a daily intake of 3 grams of HMB—an amount that’s difficult to get from food alone. That’s why supplementation is recommended, especially for aging adults or anyone at risk of sarcopenia. 

“At TSI, we believe innovation means staying ahead of the curve while also ensuring the science stands behind the story. HMB is no longer just a promising ingredient. It’s a proven solution for one of the most pressing health challenges of our time: preserving muscle and quality of life as we age,” said Shawn Baier, VP of Business Development at TSI Group. 

 

How You Can Support Muscle Health as You Age 

myHMB® is a clinically studied form of HMB designed to help support muscle health across all stages of life. As we age, maintaining muscle becomes more challenging, and that’s where myHMB® can make a difference. It works by helping to balance muscle protein turnover: encouraging muscle building while slowing muscle breakdown. This dual-action approach is what makes myHMB® a trusted option for those looking to preserve strength, support recovery, and stay active as they age. 

 

Read more about the review: 

 

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