Two groups of older men and women (> 65 years of age) were studied for 24 weeks.  One group was sedentary and one group underwent resistance training. Within each group participants were also randomized to either a placebo or HMB treatment. The researchers concluded that resistance training was an effective intervention for improving muscle strength and function in older adults, but may be of limited benefit in the population as a whole because of compliance issues.  The study also showed that HMB improves strength and muscle quality in sedentary older adults. Therefore, HMB may be a nutritional intervention to prevent sarcopenia in older adults.

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