What is HMB?

HMB stands for β-hydroxy β-methylbutyrate, which is naturally produced in our bodies during the metabolism of the essential amino acid leucine. Leucine is a part of the food chain – we eat it every day in soybeans, beef, alfalfa, and fish.


What is the difference between Calcium HMB and HMB free acid?

Calcium HMB is the mono-hydrated calcium salt combined with HMB to create a powder while the HMB free acid is HMB in its free acid liquid form.

How does HMB work?

HMB aids in increasing muscle protein in two ways:

  • Decreases protein breakdown from hard workouts.
    • HMB disrupts protein breakdown by decreasing the ubiquitin-proteasome proteolytic pathway.
  • Increases protein synthesis for increased strength.
    • Several studies indicate that HMB stimulates protein synthesis through multiple mechanisms including the mTOR pathway.

There are over 600 muscles in the human body and these muscles are responsible for all movement and support of daily living activities. Muscle is critical for our overall health and well-being.

Muscle mass peaks by about age 30, after which we normally start to lose muscle mass as we age. Muscle loss averages 0.8% per year during our 40s (about 8% per decade) and accelerates in our 70s to 1.5% per year (or 15% per decade). This translates to a loss of strength, lower energy, and slower recovery after physical training or injury. It can mean more frequent injuries and even loss of physical ability and independence.

At every stage of life and every level of activity, poor muscle health slows us down.

Bottom line, it is vital to do all we can with nutrition and exercise to keep our healthy muscle mass and strength as we age. That’s why we created myHMB — a family of ingredients and combinations clinically shown to improve muscle health. When muscle health improves, life can be lived to the fullest.

How long does it take to see results from HMB?

Studies show that measurable increases in strength and prevention for overtraining occur in only a couple of weeks; however, it will most likely take three or four weeks to produce results that will also be noticed by friends and coworkers.

How does HMB stack up scientifically?

Recognized experts at major universities have been conducting HMB research on animals and humans for over two decades. In these studies, HMB was found to have a number of beneficial effects, including producing better results faster from intense exercise. The list of HMB clinical studies is continually growing. Currently, there are about 50 human clinical studies, 40 review articles, and 4 meta-analyses, which have been published as peer-reviewed papers, and there are still more ongoing studies with HMB.

Are there any other muscle building or nutritional supplements that I should use with HMB?

It is well known that HMB can help build lean muscle mass, increase strength and improve recovery.  Recent research has shown that another nutrient, Vitamin D, is essential for helping muscles reach their full potential.  When HMB is combined with Vitamin D it optimizes the effectiveness of HMB. Learn more.

HMB combined with PEAK ATP has also shown a synergistic benefit on performance gains – meaning that when combined the benefits are greater than with either supplement alone. Learn more.

Research also shows that HMB combined with creatine produces greater results than either HMB or creatine alone.

HMB should be taken in combination with a balanced diet containing a daily protein intake of about one gram per pound of body weight, especially if you are actively exercising. If your diet isn’t balanced or your protein intake is low, then HMB should be combined with the appropriate vitamin, mineral, protein, or energy supplement to balance your diet.

Does HMB have any negative side effects?

Extensive clinical studies have been conducted to specifically evaluate the safety of HMB, and no negative side effects have been recorded in either men or women whether young or elderly. A summary of the effects of HMB on hematology, emotional profile, and adverse effects as measured in nine clinical studies showed only positive effects on cholesterol (7 percent decrease) and blood pressure (4.4 mm of Hg decrease).

What can I expect?

In clinical studies, HMB users have consistently improved strength, reduced muscle damage and have also improved body composition with exercise when compared with control test subjects. Research suggests that HMB supplementation also provides benefits to runners, cyclists, and other endurance-training individuals.

What does HMB do in the body?

HMB plays a significant role in improving the effects of training. HMB aids in increasing muscle protein in the body by decreasing protein breakdown and increasing protein synthesis. These effects have been shown to produce increases in strength, improvement in endurance, and aid in recovery from exercise/activity.

What is the recommended dosage?

The recommended dosage is three grams per day for average-size individuals. If you want to “customize” your dosage, research has shown that 38 mg/kg body weight each day is optimal.

Who can benefit from HMB supplementation?

Research indicates that HMB supplementation can benefit virtually everyone, especially those who work out and train.

Is myHMB acceptable for athletes to use in sports?

Yes, myHMB is acceptable for sports use and does not contain any banned substances in accordance to WADA (World Anti-Doping Agency).

Muscle health solutions for motivated athletes and competitors looking to get an edge in power and performance.

Whether it’s bodybuilding or cross-training, ultra-marathons, or other professional sports—training for competition is hard on your muscles. Injuries, fatigue, slow recovery, and overtraining can cause setbacks that prevent you from performing your best or even being able to compete.

With myHMB’s proven muscle health benefits, performance-driven competitors can get the edge they need to compete at a higher level.

How? Athletes can train harder, experience less fatigue, and recover more quickly after workouts. This can lead to significant increases in strength, power, and endurance to stay ahead of the competition.

Does HMB work for women?

Yes, published research results show that women who take supplemental HMB and exercise benefited from enhanced strength and improved body composition.

Who should not take HMB?

Pregnant or lactating women are advised against taking HMB because safety studies have not yet been conducted for these populations. Also, individuals with any known medical problems and adolescents should consult with their physicians prior to using HMB, as they should with all dietary supplements.

What is HMB plus vitamin D?

Researchers with the NIH conducted a year-long, double-blind study and found HMB and Vitamin D3 improved muscle function in older adults, even without exercise.

HMB boosts muscle health in older adults by both stimulating protein synthesis and reducing muscle breakdown. Higher Vitamin D3 levels are associated with greater strength and superior muscle function, especially in older adults. The study indicated that the proper ratio of HMB and Vitamin D3 can boost effects, helping improve muscle function in an entire generation of people.