GLP-1 Education and FAQ

A GLP-1 agonist is a medication that mimics the hormone GLP-1 to regulate blood sugar levels and appetite. It increases insulin secretion, reduces glucagon release, slows gastric emptying, and suppresses appetite. These drugs are used to manage type 2 diabetes and aid weight loss, with examples including liraglutide, semaglutide, and exenatide¹.

GLP-1 agonists work by mimicking the hormone GLP-1, which helps regulate blood sugar and appetite. They stimulate the pancreas to release more insulin in response to high blood sugar, reduce the release of glucagon (which raises blood sugar), slow the emptying of the stomach to promote fullness, and suppress appetite by acting on brain centers. These combined effects make GLP-1 agonists effective for managing type 2 diabetes and aiding in weight loss².

A good candidate for GLP-1 treatment is typically an adult with type 2 diabetes who struggles to control their blood sugar levels through diet, exercise, and other medications. Additionally, individuals with obesity or those who are overweight with related health conditions, such as high blood pressure or cardiovascular disease, may benefit from GLP-1 agonists due to their effects on weight loss and appetite suppression. It’s important that candidates are assessed by a healthcare provider to ensure they have no contraindications, and that GLP-1 treatment is appropriate for their specific health needs and goals³.

Taking GLP-1 agonists can lead to several side effects, including gastric dysmotility (slowed stomach emptying), nausea, and vomiting. There is a 4.5-fold increased risk of pancreatitis, which is inflammation of the pancreas. Additionally, GLP-1 agonists can cause muscle wasting and sarcopenic obesity, where muscle loss is accompanied by an increase in fat mass².

Yes, you can work out while taking GLP-1 agonists. In fact, combining these medications with regular exercise can enhance their benefits, such as improved blood sugar control and weight loss. However, it’s important to monitor how your body responds, as some people may experience side effects like nausea or dizziness that could affect their exercise routine. Always consult with your healthcare provider before starting or adjusting your workout regimen to ensure it aligns with your overall treatment plan and health status⁴.

While on a GLP-1 agonist, it’s important to prioritize a balanced diet that supports your overall health and complements the medication’s effects. Make protein a priority to help preserve lean muscle mass, as protein-rich foods promote muscle maintenance and recovery. Incorporate a variety of nutrient-dense foods, including vegetables, fruits, whole grains, and healthy fats, to ensure you’re getting essential vitamins and minerals⁵.

Additionally, consider supplementing with products and ingredients that have been shown to help maintain muscle mass while in a calorie deficit and support overall muscle health.

Results from taking GLP-1 agonists can vary, but many individuals start to see improvements in blood sugar control and weight loss within a few weeks. Typically, noticeable effects such as reduced appetite and gradual weight loss may become evident within 8-12 weeks of starting the medication. Full benefits, including more significant weight loss and improved metabolic markers, may take several months of consistent use. It’s important to follow your healthcare provider’s recommendations and be patient, as individual responses to the medication can differ⁶.