This 12-week study was conducted in college aged-men undergoing a resistance training program and supplemented with HMB (plus arginine and glutamine).   At baseline, 6, and 12 weeks an acute exercise protocol was administered. Similar to another recent study by Hoffman et al with BetaTOR HMB, HMB supplementation attenuated the inflammatory markers interferon-gamma (IFN-γ), interleukin 10 (IL-10), and interleukin 1β (IL-1β) after the acute exercise protocol.