Lipopolysaccharide (LPS) was used to simulate an endotoxemia model of muscle wasting in cultured muscle cells.  HMB was shown to attenuate the LPS-induced protein degradation. HMB attenuated the activation of caspase-3/-8, activation of dsRNA-dependant protein kinase, and production of reactive oxygen species.  This study further defined the mechanism whereby HMB may attenuate protein degradation in muscle wasting.

Back

Related Posts

Strength Training for Beginners

Strength training isn’t just for professional athletes—it’s a powerful way for anyone to boost long-term strength, energy, and confidence. Whether…

Read More