Change in plasma ß-hydroxy-ß-methylbutyrate (HMB) by feeding leucine, alpha-ketoisocaproate (KIC), and isovaleric acid (IVA) to pigs
Feeding leucine and KIC increased plasma HMB levels to that seen when HMB is fed. Feeding IVA also increased HMB…
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Effect of feeding ß-hydroxy-ß-methylbutyrate (HMB) on leucine and fat metabolism in mammary gland
HMB increased milk fat percentage in lactating goats.
Uptake and output of the leucine metabolite ß-hydroxy-ß-methylbutyrate (HMB) across the leg of pigs
HMB is produced across the hind legs of pigs when high levels of leucine are fed.
Effect of ß-hydroxy-ß-methylbutyrate on the health and performance of shipping stressed calves
HMB decreased morbidity by 40 percent and mortality by 50 percent in young stressed calves (four studies).
Oxidation of leucine and alpha-ketoisocaproate to beta-hydroxy-beta-methylbutyrate in vivo.
HMB is produced in the body from leucine and KIC in sheep and pigs.
Leucine and its catabolites alter mitogen-stimulated DNA synthesis by bovine lymphocytes.
In vitro leucine was shown to suppress lymphocyte function while HMB tended to increase function. HMB did not substitute for…
