In a recent interview with Nutraceuticals World, Shawn Baier, VP of Business Development at TSI Group, discussed the significance of muscle maintenance during weight loss regimens and introduced a potential solution: myHMB®.

Weight Loss Vs. Fat Loss

Baier emphasized the distinction between weight loss and fat loss, highlighting the necessity of preserving muscle mass for long-term fat loss success. He noted that traditional weight loss methods, particularly those involving GLP-1 receptor antagonists (Ras), can lead to muscle breakdown alongside fat loss, which poses challenges for sustained fat loss.


The Solution: myHMB®

Enter myHMB®, a supplement scientifically known as β-hydroxy β-methylbutyrate (HMB), is a downstream metabolite of the amino acid leucine. Baier explained that myHMB® works by increasing muscle protein synthesis and reducing muscle protein breakdown, effectively aiding muscle maintenance during periods of metabolism or high stress.

Clinical studies have shown HMB’s efficacy in various scenarios, including bed-rest patients, athletes undergoing weight cutting for competitions, and individuals on calorie-restricted diets. Results indicate a higher percentage of fat loss compared to muscle loss, aligning with the ultimate goal of fat loss.


Why use HMB with GLP-1 RAs

Baier also highlighted HMB’s potential synergy with GLP-1 RAs for enhanced fat loss. While more research is needed in this area, preliminary data suggests promising outcomes when combining HMB supplementation with GLP-1 RAs.


Proven Quality

Quality assurance is paramount for TSI Group, with myHMB® boasting USP verification, NSF, and GMP certifications. Beyond individuals seeking fat loss, Baier suggested that athletes, those focused on body composition, aging adults, and individuals recovering from trauma or illness could benefit from HMB supplementation.

Product Versatility

Product formulators can leverage myHMB®‘s versatility, as it is compatible with various formulations, including bars, drink mixes, capsules, tablets, soft gels, liquid caps, and even gummies.



With the rise of interest in weight loss solutions, myHMB® offers a promising avenue for preserving muscle mass and achieving long-term fat loss goals. As the conversation around fat loss evolves, myHMB® stands out as a potential game-changer in the pursuit of a healthier lifestyle.

Link to the full interview

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