The Effect of β-Hydroxy-β-Methylbutyrate on Aerobic Capacity and Body Composition in Trained Athletes.
In this study HMB was supplemented in a double-blinded, placebo-controlled, crossover design in 58 highly trained males. To qualify the…
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Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes
This significant study performed in skeletal muscle cells shows that leucine’s stimulation of protein synthesis in muscle is through conversion…
β-Hydroxy-β-methylbutyrate attenuates cytokine response during sustained military training.
Military training is some of the most strenuous training an individual can undergo. Sleep deprivation coupled with a high level…
The addition of beta-hydroxy-beta-methylbutyrate and isomaltulose to whey protein improves recovery from highly demanding resistance exercise.
This study in resistance-trained college-aged men measured recovery from 3 consecutive days of intense resistance training. The training regimen consisted…
The efficacy of a β-hydroxy-β-methylbutyrate supplementation on physical capacity, body composition and biochemical markers in elite rowers: a randomised, double-blind, placebo-controlled crossover study.
Sixteen elite rowers were supplemented with HMB for 12 weeks in a double-blind, placebo-controlled, crossover study. VO2max increased with HMB…
Comparison of availability and plasma clearance rates of β-hydroxy-β-methylbutyrate delivery in the free acid and calcium salt forms
The free acid form of HMB (BetaTOR) is available in commercially produced capsules similar to that of CaHMB. Therefore this…
Effects of β-Hydroxy-β-methylbutyrate Free Acid Ingestion and Resistance Exercise on the Acute Endocrine Response
In this study the researchers looked at the endocrine response after an acute heavy resistance exercise protocol. Twenty resistance-trained subjects…
β-Hydroxy-β-methylbutyrate (HMB) supplementation and resistance exercise significantly reduce abdominal adiposity in healthy elderly men.
This study looked at the effect of 12 weeks of HMB supplementation, with and without resistance training (RT), on abdominal…
Effect of beta-hydroxy-beta-methylbutyrate supplementation on muscle loss in older adults: a systematic review and meta-analysis.
The authors examined seven clinical trials, performing a meta-analysis which included data from 147 HMB-supplemented and 140 control supplemented adults…
Influence of HMB supplementation and resistance training on cytokine responses to resistance exercise.
This 12-week study was conducted in college aged-men undergoing a resistance training program and supplemented with HMB (plus arginine and…
