Signaling pathways initiated by beta-hydroxy-beta-methylbutyrate to attenuate the depression of protein synthesis in skeletal muscle in response to cachectic stimuli.

Protein synthesis studies were conducted in a cachectic mouse model and in muscle cell cultures.   The results demonstrate that HMB…

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Supplementation with beta-hydroxy-beta-methylbutyrate (HMB) and alpha-ketoisocaproic acid (KIC) reduces signs and symptoms of exercise-induced muscle damage in man.

This counterbalanced, crossover study in 6 non-resistance trained males given either a placebo or HMB/KIC (3 grams HMB and 0.3…

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Effect of beta-hydroxy-beta-methylbutyrate, arginine, and lysine supplementation on strength, functionality, body composition, and protein metabolism in elderly women.

In two independent double-blind, randomized, placebo-controlled clinical studies in elderly women, data from both of the studies studies demonstrate that…

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Supplementation with a combination of beta-hydroxy-beta-methylbutyrate (HMB), arginine, and glutamine is safe and could improve hematological parameters.

Consumption of HMB, arginine, and glutamine by healthy, AIDS patients and cancer patients was studied.  No adverse effects were seen…

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