Lipopolysaccharide (LPS) was used to simulate an endotoxemia model of muscle wasting in cultured muscle cells. HMB was shown to…
HMB supplementation was given either pre- (60 min to allow blood levels to increase) or post-exercise to college-aged men performing…
In this study tissue as well as whole body protein turnover was studied in rats after HMB administration. This study…
This review finds that HMB is one of the safest and supplements for increasing athletic performance. These authors review current…
This independent, peer-reviewed paper discusses the critical details of HMB studies and the variables affecting the results of these studies.…
This 8-week study using a rat tumor model showed that oral HMB attenuated the cachexic weight loss caused by the…
The author’s first paper detailed HMB effect on maintaining protein synthesis even after administration of lipopolysaccharide, TNF-α and angiotensin II.…
Subjects’ ethical backgrounds prevented this study from being conducted as a double-blind, placebo-controlled study; however, a placebo treatment was utilized.…
This placebo-controlled, double-blind clinical study of HMB in critically injured patients suggests that HMB can improve nitrogen balance in severely…
This chapter in the CRC series of desk references for professional nutritionists and trainers discusses the origins, mechanisms, uses, safety,…