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Research By Focus

Body Composition

Calcium Beta-Hydroxy-Beta-Methylbutyrate-Enriched Nutritional Supplementation During Dietary Weight Loss in Adults With Obesity: A Randomized Controlled Trial

In this randomized, double-blind, controlled trial, 102 adults with obesity followed a standardized calorie-restricted diet for 12 weeks while receiving either a daily CaHMB-enriched nutritional supplement providing 3 g of CaHMB and 24 g of protein or an energy-matched control. Participants receiving the CaHMB-enriched supplement maintained skeletal muscle mass, while the control group experienced muscle loss, resulting in a significant between-group difference of 1.3 kg. The CaHMB-enriched group also experienced greater reductions in body fat mass and visceral fat area and better preservation of basal metabolic rate. These findings suggest that CaHMB-enriched nutrition may support muscle preservation and more favorable body composition during dietary weight loss. Because the supplement contained protein and additional nutrients alongside CaHMB, the findings reflect the nutritional formula as a whole.

The effect of supplementation of HMB (β-hydroxy β-methylbutyrate) and plyometric exercises on performance and body composition of elite parkour athletes in Tehran.

In this 2022 study, researchers examined whether HMB supplementation combined with plyometric training influenced body composition, agility, and standing jump power in elite parkour athletes. Parkour requires explosive lower-body power, strength, and agility, making this a relevant model for studying performance-focused training adaptations. The study suggests that HMB, when paired with structured plyometric exercise, may help support body composition and performance outcomes in elite parkour athletes.

Time-restricted feeding plus resistance training in active females: a randomized trial.

The effects of HMB supplementation during 8 weeks of time-restricted feeding were studied in young, resistance-trained women. Time-restricted feeding is a type of intermittent fasting, where all daily calories are consumed during a smaller “feeding window” each day. Each study participant was assigned to either time-restricted feeding (TRF, 8 hours) or the control group (no feeding time restrictions). Half of the women in the TRF group took three 1g doses of HMB per day (upon waking, mid-morning, and at bedtime), while all other participants took placebo supplements on the same schedule.  All of the women completed the same whole-body resistance training program. 24 women completed the entire study as designed. In these women, fat free mass and muscle thickness increased in all three groups. However, only the TRF+HMB group significantly reduced fat mass (-7%) and significantly improved their body composition (-2.3 % body fat, an 8% improvement). These data show that HMB can help reduce body fat while maintaining muscle mass during intermittent fasting in active women.