Research By Year

2011

The effect of HMB supplementation on body composition, fitness, hormonal and inflammatory mediators in elite adolescent volleyball players: a prospective randomized, double-blind, placebo-controlled study.

This randomized, double-blind, placebo-controlled study examined HMB supplementation in young male and female elite volleyball players for 7 wks.  HMB supplementation resulted in improved body composition and significantly increased strength, while also decreasing fat mass percentage. HMB supplementation also increased peak and mean anaerobic power.  No changes in hormones or inflammatory mediators were seen in this study.

Vitamin D status affects strength gains in older adults supplemented with a combination of β-hydroxy-β-methylbutyrate, arginine, and lysine: a cohort study.

This year-long retrospective study in elderly adults demonstrated that a nutrient mixture of HMB, arginine, and lysine alone was effective in improving body composition regardless of vitamin D status, but accompanying strength increases were observed only when participants also had adequate vitamin D status indicating a synergistic effect between the HMB, arginine, and lysine and vitamin D.

Free acid gel form of β-hydroxy-β-methylbutyrate (HMB) improves HMB clearance from plasma in human subjects compared with the calcium HMB salt.

The results of this research study demonstrate that a liquid gel form of HMB is more readily available to tissues when taken orally than the currently available powdered form, Calcium HMB. The results show quicker and higher plasma levels of HMB with improved utilization by the tissues. HMB free acid gel could improve HMB availability and efficacy to tissues in health and disease.