Two double-blind, placebo-controlled, randomized studies were conducted in weight training males. In these separate studies, one for three weeks and one for seven weeks, it was found that supplementing three grams of HMB to exercising humans improved body composition, increased strength, and reduced muscle damage.
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1996
Calcium beta-hydroxy-beta-methylbutyrate. 1. Potential role as a phosphate binder in uremia: in vitro study.
Calcium HMB is as efficient as calcium acetate in binding phosphate in vitro, which may predict its effective role in vivo. HMB may be effective in lowering phosphate in uremia.