In two independent double-blind, randomized, placebo-controlled clinical studies in elderly women, data from both of the studies studies demonstrate that a nutritional mixture of HMB, arginine, and lysine can enhance whole body protein synthesis and improve functionality in elderly women.
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2004
Mechanism of the attenuation of proteolysis-inducing factor stimulated protein degradation in muscle by beta-hydroxy-beta-methylbutyrate.
This In vitro study of chemical markers of proteolytic functions in muscle cell cultures showed that HMB inhibits activation of a major protease pathway in muscle, thus inhibiting protein degradation in muscle.
Supplementation with a combination of beta-hydroxy-beta-methylbutyrate (HMB), arginine, and glutamine is safe and could improve hematological parameters.
Consumption of HMB, arginine, and glutamine by healthy, AIDS patients and cancer patients was studied. No adverse effects were seen and the mixture enhanced hematological parameters such as red blood cell numbers.
