Sixteen elite rowers were supplemented with HMB for 12 weeks in a double-blind, placebo-controlled, crossover study. VO2max increased with HMB supplementation as well as time to ventilatory threshold, threshold load, and threshold heart rate. The researchers concluded that supplementing with HMB was advantageous for endurance athletes in increasing aerobic capacity and power.
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The efficacy of a β-hydroxy-β-methylbutyrate supplementation on physical capacity, body composition and biochemical markers in elite rowers: a randomised, double-blind, placebo-controlled crossover study.
Effects of beta-hydroxy-beta-methylbutyrate on aerobic-performance components and body composition in college students.
In this placebo-controlled study in interval-training college students, HMB supplementation was shown to significantly increase maximal oxygen consumption and respiratory compensation point.
Effect of beta-hydroxy beta-methylbutyrate on the onset of blood lactate accumulation and V(O)(2) peak in endurance-trained cyclists.
This double-blind switchback study with HMB, leucine, and placebo showed that HMB supplementation increased the cyclists endurance as measured by VO2 peak and lactate threshold.
This double-blind randomized study in male and female runners showed that HMB reduced muscle damage after a prolonged run. Decreasing the amount of muscle damage caused by running may decrease the DOMS soreness many long-distance runners experience.